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Urologic Surgery Trials

For enrollment information involving the following trials, please contact one of the research staff members listed on Meet the Team.

Perioperative Physical Activity (Pedometer)

Frailty Study

Seminoma


Perioperative Physical Activity (Pedometer)

Prospective Randomized Study of Exercise in Patients Undergoing Urologic Surgery

Inclusion Criteria:

  • Adult patients scheduled for operative procedure with an inpatient postoperative stay

  • Willing and able to give blood samples, complete a questionnaire, fill out the step log, and return to clinic for 1st post-operative appointment

Exclusion Criteria:

  • None

Treatment:

Patients are given a pedometer and asked to record their daily steps in a log. The purpose of this study is to determine if pedometers can aid in increasing patients' physical activity during the perioperative period.

Principal Investigators: Kenneth Ogan, MD; Viraj Master, MD, PhD; John Pattaras, MD; Peter Nieh, MD


Frailty Study

Frailty as a Predictor of Outcomes in Surgical Patients

Inclusion Criteria:

  • Patients already scheduled for major surgery requiring an overnight hospital stay that are willing to do the study’s preoperative assessment tools

  • Patients must be able to give informed consent and be 18 years and older

Exclusion Criteria:

  • Patients diagnosed with severe dementia, Parkinson’s disease, or other functional motor disorders

  • Patients diagnosed with a stroke and who have residual motor and/or cognitive deficits

  • Patients taking carbidopa/levodopa, donepezil hydrochloride, or antidepressant medications

Principal Investigators: Kenneth Ogan, MD; Viraj Master, MD, PhD

Co-Investigators & Collaborators: John Pattaras, MD; Peter Nieh, MD, and four surgeons from the Department of Surgery: John Sweeney, MD; David Kooby, MD; Shishir Maithel, MD; Shipra Arya, MD


Seminoma

Phase II Trial of Retroperitoneal Lymph Node Dissection as First-Line Treatment for Testicular Seminoma with Isolated Retroperitoneal Disease (1-2cm)

Inclusion Criteria:

  • Pure seminoma after orchiectomy presenting with isolated retroperitoneal lymphadenopathy

  • Normal serum AFP, β-HCG, LDH (per the local laboratory assay) within 14 days of RPLND

  • Primary tumor excised by radical inguinal orchiectomy and pathology consistent with pure seminoma with negative surgical margins

  • Chest imaging negative for metastasis no more than six weeks prior to the date of RPLND

Exclusion Criteria:

  • Second primary malignancy OR any history of serum AFP elevation

  • Patients receiving any other investigational agent(s)

  • History of receiving chemotherapy or radiotherapy

  • Uncontrolled intercurrent illness: ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness

Principal Investigator: Mehrdad Alemozaffar, MD

Co-Investigator & Collaborator: Viraj Master, MD, PhD

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